Sunday, March 21, 2010

Papaver Somniferum

Today, people search the ‘Net for naturally-occurring medicines. A patchwork quilt of information suggests this quest is as old as time. Records indicate a variety of plant drugs were used by early civilizations. These peoples sought out the psychological boost of alcohol, tobacco or opium.

There were several variations of the benefits from a plant-derivative intoxication. The drug-induced state was sometimes used to see visions of the future. As medical knowledge expanded by discovery and conjecture, it was believed that one could remove the mental or physical symptoms that were caused by an imbalance of the Ancient Greek humors of blood, bile and phlegm by cleansing superfluous humors from the brain. One natural medicine in particular can be dated back to the earliest human settlements: the opium poppy Papaver Somniferum.

The earliest relationship between people and the opium poppy dates back to the Sumerians of approximately 3300 B.C. The Sumerians were one of the world’s first organized faming communities. They harvested the opium poppy as one of their many main crops. The Sumerians are credited with the invention of writing in the Middle East. They recorded using the opium poppy Papaver Somniferum for medicine and pleasure. The Sumerians called Papaver Somniferum the “plant of joy”. They used opium from the poppy to induce the same intoxicated and relaxed conditions as the manufacture of beer from barley crops. The poppy plant was also commonly used and traded at this time for its value as a supply of food, animal fodder oil and fuel.

The value of opium from the Papaver Somniferum poppy spread along trading routes from the Persian Gulf all the way to Greece. The records of the Greek physician Hippocrates contain prescriptions for the healing power of opium to cure insomnia. Other physicians would later agree with Hippocrates’ views on opium. Galen advocated eating opium as well as vegetable therapies. Dioscorides described how opium mixed with a liquid was a valuable medicine for added strength. Dioscorides described how the pod of the poppy could be crushed and mixed with the liquid. He is credited with proposing that the word “nepenthes” in a passage from Homer’s Oddessy may have been a drug mixture that included opium.

The apparent magic of the poppy’s ability to induce a drowsy state comes from morphine that is the principal active ingredient in opium. Raw opium contains a concentration of three to twenty percent morphine depending on its cultivation and processing.

The most common means of taking opium was called a liquid elixir. The raw opium milk found in the seed pod was mixed with wine or water. This liquid did not cure the patient but the dreamy euphoric state helped lessen the patient’s pain. The early Greeks believed that the physical world around them was tightly connected to the quality of life provided by the gods. The abundance of poppy seeds in the dried poppy pod was seen as a sign of fertility by the Greeks.

The poppy spread east to India and China along trading routes during the seventh century. The Chinese welcomed the wonder of the poppy seed mixed with bamboo juice. The Chinese felt this mixture offered a tremendous healing power.

Present day findings have classified opium as a drug that dulls the senses and has listed opium as a narcotic. As narcotics opium, morphine and heroin are drugs that relieve pain, relax spasms, reduce fevers and induce sleep.

Up to this point, the spread of the poppy seed had been very slow over land-based trading routes. The European development of ocean-going sailing ships rapidly expanded the introduction of opium into England and the United States. The wealthy class in Britain regularly consumed opium to relieve pain. Members of the British Royalty took opium to relieve a variety of aliments.

As use of opium spread, it was used to “treat” piles, chitis, cholera, dysentery, bronchitis, earaches and measles. The opium products calmed the patients and the temporary relief from pain caused an appearance of regaining good health. At this time, opium was called a ‘stimulant” because opium was considered to be a jump-start to well-being.

The search for medicines that could at least temporarily relieve pain in the 1700 and 1800s was sought by every developing nation. Opium was commonly consumed to get some relief from dropsy, consumption (tuberculosis) and rheumatism (rheumatoid arthritis). Britain and the United Nations imported hundreds of thousands of pounds of opium to meet the demand.

In these two countries the people preferred taking opium as a liquid known a s “Laudanum” or “black drop”. Laudanum was usually an opium-alcohol mixture. Another variation of Laudanum, Laudanum Cydoniatum, was made from a mixture of opium and vinegar. In Britain, Laudanum was very inexpensive and could be bought as easily as acetaminophen today. It was even sold in grocery stores as a medically-acknowledged temporary relief from coughing and pain. Records of bills from San Francisco to Vancouver show opium to be considered a grocery staple along with sugar, rice and tea.

Another form of use was a pill composed of opium, sweetened with saffron, castor, ambergris, musk and nutmeg to disguise the bitter opium taste. The opium pill was considered so safe that pregnant women could use it to control morning sickness.

In the 19th century opium was commonly listed as one of the ingredients in a wide range of patent medicines. A product called Ayers Cherry Pectoral contained opium as one of its key ingredients. This product was readily available to thousands of British and American parents to sooth babies who were crying due to teething, hunger or pains of childhood. Cough syrups in the mid-nineteenth century usually contained opium. Opium is still considered to be unsurpassed as a cough suppressant.

In 1931 Louis Lewin recorded opiates as a drug that sedated mental activity. He classified this sedation as “Euphorica”. Today the chemical properties of Papaver Somniferum are well documented, including images of changes to the brain activity. The search for naturally-occurring medicines continues in the rainforests and oceans of the world.

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